Oxygen-18 (O-18) – Stable Isotope Data & Safety Information (MSDS)

Stable Isotopes for Oxygen-18 (O-18) – Material Safety Data Sheet (MSDS)

SECTION 1: IDENTIFICATION

Product Name: Oxygen-18 (O-18)

Chemical Formula: O₂ (enriched in ¹⁸O)

CAS Number: 32767-36-5

Molecular Weight: 36.00 g/mol (approx., for O₂ enriched in ¹⁸O)

Synonyms: ¹⁸Oxygen, O-18 isotope, Enriched Oxygen-18

Intended Use: Laboratory research, radiopharmaceutical production (e.g. F-18), medical imaging, nuclear science

Manufacturer/Supplier Information:

• Company Name: Nakima Ltd
  
• Telephone: +971-52-5156232
  
• Website: www.isotope-amt.com
  

SECTION 2: HAZARD IDENTIFICATION

Classification of the substance or mixture

Classification according to Regulation (EC) No. 1272/2008 [CLP]

• Oxidizing gas – Category 1 (H270)
  
• Gases under pressure – Compressed gas (H280)
  

Classification according to Directive 67/548/EEC [DSD] or 1999/45/EC [DPD]

• Not classified
  

GHS-US classification

• Oxidizing gas (H270)
  
• Compressed gas (H280)
  

Signal Word: Danger

Hazard Statements:

• H270: May cause or intensify fire; oxidizer
  
• H280: Contains gas under pressure; may explode if heated
  

Precautionary Statements:

• P220: Keep away from combustible materials
  
• P244: Keep valves and fittings free from oil and grease
  
• P410 + P403: Protect from sunlight. Store in a well-ventilated place
  

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

SECTION 4: FIRST AID MEASURES

• Inhalation: Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention if symptoms persist.
  
• Skin Contact: Not applicable under normal conditions.
  
• Eye Contact: Not applicable.
  
• Ingestion: Not applicable.
  

SECTION 5: FIRE-FIGHTING MEASURES

• Suitable Extinguishing Media: Use extinguishing media appropriate for surrounding fire.
  
• Unsuitable Extinguishing Media: None known.
  
• Hazardous Combustion Products: Oxygen enrichment can intensify combustion.
  
• Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear.
  

SECTION 6: ACCIDENTAL RELEASE MEASURES

• Personal Precautions: Ensure adequate ventilation. Evacuate area if needed.
  
• Environmental Precautions: Prevent accumulation in confined spaces.
  
• Cleanup Methods: Ventilate area. Eliminate ignition sources. Stop release if safe.
  

SECTION 7: HANDLING AND STORAGE

• Handling: Use with proper ventilation. Avoid contact with grease or oil.
  
• Storage Conditions: Store in a cool, dry, well-ventilated place. Keep cylinders upright and secure. Avoid sources of ignition.
  

SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION

• Occupational Exposure Limits: None established.
  
• Engineering Controls: Use appropriate exhaust ventilation.
  
• Personal Protective Equipment (PPE):
  
  • Eye Protection: Safety goggles when handling pressurized containers
    
  • Skin Protection: Not required under normal use
    
  • Respiratory Protection: Use protection if ventilation is inadequate
    

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES

• Appearance: Colorless gas
  
• Odor: Odorless
  
• Melting Point: -218.8 °C
  
• Boiling Point: -183.0 °C
  
• Solubility: Slightly soluble in water
  
• Density: 1.429 g/L (at 0°C and 1 atm)
  
• Autoignition Temperature: Not applicable
  

SECTION 10: STABILITY AND REACTIVITY

• Reactivity: Strong oxidizer
  
• Chemical Stability: Stable under normal conditions
  
• Incompatible Materials: Organic materials, oils, grease, flammable gases
  
• Hazardous Decomposition Products: None
  

SECTION 11: TOXICOLOGICAL INFORMATION

• Acute Toxicity: Not toxic
  
• Carcinogenicity: Not classified
  
• Routes of Exposure: Inhalation
  
• Symptoms: High concentrations can displace oxygen, leading to dizziness or suffocation
  

SECTION 12: ECOLOGICAL INFORMATION

• Ecotoxicity: Not environmentally hazardous
  
• Persistence and Degradability: Not applicable
  
• Bioaccumulative Potential: Not applicable
  
• Mobility in Soil: Gas phase
  

SECTION 13: DISPOSAL CONSIDERATIONS

Dispose of in accordance with local, state, and federal regulat

SECTION 14: TRANSPORT INFORMATION

• UN Number: UN1072
• Proper Shipping Name: Oxygen, compressed
• Transport Hazard Class: 2.2
• Packing Group: Not applicable

SECTION 15: REGULATORY INFORMATION

• EU Regulations: Classified as oxidizer and compressed gas
• US TSCA Status: Listed
• OSHA Hazard Classification: Oxidizer, Compressed Gas

SECTION 16: OTHER INFORMATION

Disclaimer: The information provided here is believed to be accurate but is not guaranteed. It is the responsibility of the user to ensure safe handling and compliance with applicable regulations.

Revision Date: March 2025

Prepared by: Nakima Ltd