Zinc-68 (Zn-68): stable isotope Properties and Applications

Zinc-68 (Zn-68): Stable Isotope Properties and Applications

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Introduction

Zinc-68 (Zn-68) is a stable, non-radioactive isotope of zinc, accounting for approximately 18.8% of naturally occurring zinc. With 30 protons and 38 neutrons, Zn-68 is widely used in the fields of nuclear medicine, diagnostics, and cyclotron-based radioisotope production.

Its high natural abundance and excellent nuclear properties make Zn-68 particularly valuable as a precursor for generating Gallium-68 (Ga-68), a short-lived positron-emitting radioisotope used in PET imaging.


Physical and Nuclear Properties

  • Symbol: Zn-68

  • Atomic Number (Z): 30

  • Mass Number (A): 68

  • Isotopic Mass: 67.924844 u

  • Natural Abundance: ~18.8%

  • Stability: Stable (non-radioactive)


Key Applications

1. Production of Gallium-68 (Ga-68)

Zn-68 is used as a target material in cyclotrons to produce Ga-68 via the (p,n) nuclear reaction. Ga-68 is one of the most widely used PET imaging isotopes, especially in the diagnosis of neuroendocrine tumors and prostate cancer using Ga-68-labeled radiopharmaceuticals.

2. Nuclear Medicine and Diagnostics

Through Ga-68 production, Zn-68 indirectly supports the development of advanced radiotracers for imaging and theranostics. This makes Zn-68 an essential component in nuclear medicine supply chains.

3. Research and Development

Enriched Zn-68 is used in research involving nuclear reactions, neutron activation studies, and the optimization of radiopharmaceutical production processes.


Where to Buy Zinc-68

High-purity Zinc-68 is available from isotope suppliers in metallic or oxide form, optimized for cyclotron targets and research use.

Nakima Ltd supplies enriched Zn-68 in multiple formats, offering:

  • Purity levels >99%

  • Forms: Metallic foil, powder, or ZnO

  • Certified isotopic composition and documentation

  • Packaging compliant with international standards for transport and safety


Future Outlook

With the increasing clinical demand for Ga-68-based PET imaging, Zn-68 is expected to remain in high demand. Its importance in enabling decentralized Ga-68 production at medical centers and cyclotron facilities ensures that it will continue to be a strategic isotope in nuclear healthcare.


Interested in Zn-68 for PET imaging or isotope production? Contact Nakima Ltd for expert supply of enriched Zinc-68 isotopes.

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